Casodex is indicated for use in combination therapy with a luteinizing hormone-releasing hormone analog for the treatment of Stage D2 metastatic carcinoma of the prostate.

INSTRUCTIONS

Take Casodex exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Casodex is given as part of a combination prostate cancer treatment with another medication called a luteinizing (LOO-tee-in-ize-ing) hormone-releasing hormone, or LHRH. This medication prevents the testicles from producing testosterone.

Treatment with Casodex and LHRH is usually started at the same time. Follow your doctor’s instructions.

Casodex is usually taken once per day in the morning or evening. You may take the medicine with or without food. Try to take the medication at the same time each day.

LHRH is given as an injection or a tiny implant injected through a needle under the skin around your navel. LHRH injections are given at intervals such as once every 4 weeks. Follow your doctor’s instructions.

Your doctor may occasionally change your dose to make sure you get the best results. Do not stop taking Casodex without your doctor’s advice. If you stop your treatment suddenly, your condition may become worse.

To be sure this medication is helping your condition and is not causing harmful effects, your prostate and liver function will need to be checked with frequent blood tests. Do not miss any scheduled appointments.

If you miss a dose – take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose.

DOSAGE

The recommended dose for Casodex (bicalutamide) therapy in combination with an LHRH analog is one 50 mg tablet once daily (morning or evening), with or without food. It is recommended that CASODEX (bicalutamide) be taken at the same time each day. Treatment with Casodex (bicalutamide) should be started at the same time as treatment with an LHRH analog.

STORAGE

Store at controlled room temperature, 20°-25°C (68°-77°F).